Discover Your Perfect Cayo Guillermo Vacation Homes

Best Vacation Homes in Cayo Guillermo

10.0 (2 Reviews)
House
  • TV
  • Balcony/Terrace
  • Bedding/Linens
10.0 (1 Review)
House
  • Air Conditioner
  • Balcony/Terrace
  • Accessibility
9.6 (10 Reviews)
House
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
9.0 (4 Reviews)
House
  • Air Conditioner
  • Parking
  • Balcony/Terrace
8.0 (1 Review)
Bed & Breakfast
  • Pool
  • Balcony/Terrace
  • Bedding/Linens
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6.0 (3 Reviews)
House
  • Air Conditioner
  • Wheelchair Accessible
  • Balcony/Terrace

Why Choose Rent By Owner for your Cayo Guillermo Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Cayo Guillermo

When should you plan your Vacation Rentals stay?

Choosing the ideal time to visit this destination can enhance your experience, as the weather and local events here vary throughout the year, helping you plan your stay for optimal enjoyment of the region's natural beauty and tranquil beaches.

Peak Season Highlights

spring
December to April

During the peak season from December through April, you can enjoy the warm and sunny weather ideal for exploring the area’s beaches and outdoor activities. This is when the region experiences the highest demand for vacation rentals.

Average Temperature Daytime: around 28°C (82°F) - Nighttime: around 20°C (68°F)
spring
July to August

The summer months of July and August mark another peak period when visitors flock to enjoy the lush scenery and vibrant marine life here. Expect higher occupancy rates and more lively atmosphere in your vacation rental.

Average Temperature Daytime: around 31°C (88°F) - Nighttime: around 24°C (75°F)

Off-Season Highlights

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May to June

In late spring to early summer, before the summer rush begins, this is a quieter time for visiting the region. You may find more availability and better rates on vacation rentals while enjoying comfortable weather.

Average Temperature Daytime: around 29°C (84°F) - Nighttime: around 22°C (72°F)
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September to November

Late fall offers a peaceful escape as the region transitions into its less busy period. Experience calmer surroundings and favorable weather conditions that are perfect for a relaxed getaway.

Average Temperature Daytime: around 28°C (82°F) - Nighttime: around 21°C (70°F)

Weekly Weather Forecast for Cayo Guillermo

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy access to private or shared outdoor pools, perfect for relaxing under the sun.
  • Take advantage of well-maintained outdoor seating areas and loungers to unwind outdoors.
  • Benefit from lush gardens or landscaped yards that add natural beauty to your stay.
  • Make use of barbecue grills and outdoor dining spaces for alfresco meals.
  • Explore nearby beaches with direct access for swimming, sunbathing, and water activities.
  • Utilize shaded patios or verandas ideal for enjoying the warm climate.
  • Participate in outdoor recreational activities such as tennis or volleyball courts available at some properties.
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Family Activities

  • Snorkeling and Beach Exploration: Experience the vibrant marine life and pristine beaches by exploring the clear waters just off the shore, making it a perfect family activity in this scenic region.
  • Wildlife Watching Tours: Enjoy guided excursions that showcase the area's rich birdlife and natural habitats, offering educational fun for children and adults alike.
  • Water Sports Activities: Engage in safe and exciting water adventures such as kayaking or paddleboarding, ideal for families seeking active leisure amid beautiful surroundings.
  • Relaxing at Family-Friendly Resorts: Spend quality time together at local resorts with kid-friendly amenities, pools, and entertainment options designed to ensure a memorable stay here.
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Adult Activities

  • Snorkeling and Diving: Discover the vibrant marine life just offshore by exploring the crystal-clear waters that surround this tropical island destination.
  • Sunset Cruises: Enjoy a relaxing evening on the water with a sunset cruise, offering breathtaking views over the area's picturesque coastline.
  • Beachside Relaxation: Unwind on pristine, white sandy beaches where you can bask in the sun or take a refreshing swim in the calm Caribbean waters.
  • Local Cuisine Tasting: Savor authentic Cuban flavors by visiting nearby eateries that serve regional dishes, making your stay here even more memorable.

Other Places to Stay in Cayo Guillermo

Cayo Guillermo Travel Tips

How Can You Make the Most of Your Stay?

  • Explore the beaches: Take full advantage of the pristine shores here by planning your days around sunbathing, swimming, and engaging in water sports to enjoy the region's natural beauty.
  • Experience local cuisine: Savor authentic flavors at nearby eateries or within your vacation rental to immerse yourself in the regional culinary culture.
  • Engage in outdoor activities: Make the most of outdoor adventures such as snorkeling, boat trips, or nature walks that highlight the area's stunning landscapes and marine life.
  • Customize your stay: Choose a well-located vacation rental that offers privacy and amenities tailored to your preferences, ensuring a personalized and relaxing experience throughout your visit.

Transportation Options

  • Private Taxi Services: You can hire private taxis for convenient and flexible transportation around the area and to nearby destinations.
  • Car Rentals: Renting a vehicle gives you the freedom to explore the region at your own pace with numerous rental agencies available on the island.
  • Local Buses: Public bus services offer an affordable way for travelers to navigate between key points of interest within this destination.
  • Shuttle Services: Many resorts and vacation rentals provide shuttle options that ensure easy access to local beaches and amenities without hassle.

Local Customs Options

  • Greeting Etiquette: It is customary to greet locals with a warm handshake or a friendly nod when you arrive in this destination, reflecting the region’s welcoming spirit.
  • Music and Dance Appreciation: Embracing the lively rhythms and dance traditions here shows respect for the local culture and enhances your experience of the area.
  • Respect for Nature: Visitors are encouraged to conserve the natural beauty by avoiding littering and being mindful of the environment during your stay in this region.
  • Community Interaction: Engaging with residents politely and showing genuine interest in their customs helps foster meaningful connections in this destination.

Frequently Asked Questions About Cayo Guillermo?

1. What are the top vacation rentals in Cayo Guillermo?

There are a lot of options in Cayo Guillermo. If you plan on staying in the Cayo Guillermo area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Cayo Guillermo:

2. Which vacation homes in Cayo Guillermo are best for families?

If you are looking for a family-friendly vacation home in Cayo Guillermo, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Cayo Guillermo:

3. How many Rentbyowner vacation rentals are available in Cayo Guillermo?

Currently, the total number of properties listed by Rent By Owner in 2025 is over 45 in the Cayo Guillermo area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Cayo Guillermo. 

4. What is the cancellation policy for vacation rentals in this area?

Cancellation policies vary depending on the individual property listing. You should review the specific policy outlined by the owner before booking, as terms may include refundable or non-refundable options.

5. How do I contact the owner of a vacation rental in this region for special requests?

You can directly message the property owner through the booking platform to discuss any special requests or questions about your stay. Owner contact details are typically provided once your reservation is confirmed.

6. Are there any additional fees I should be aware of when booking here?

Additional fees such as cleaning charges, security deposits, or city taxes may apply and are detailed in each property's listing. Be sure to review these fees before completing your reservation.

7. Is early check-in or late check-out available at vacation rentals around here?

Availability of early check-in or late check-out depends on the host's policies and the property's schedule. It’s recommended to request these options in advance to ensure your convenience.

8. What amenities are typically included in vacation rentals in this destination?

Most properties offer essential amenities such as Wi-Fi, air conditioning, and kitchen facilities. Specific amenities vary by listing, so check each property’s description for detailed information.