Discover Your Perfect Mytilene Vacation Homes

Best Vacation Homes in Mytilene

Villa
Map-icon
like-icon10.0
Exceptional
(19 Reviews)
1 Bedroom 1 Bath 4 Guests 592 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Ocean View
    Ocean View
More amenities
£169/Night 7 Nights - £1,185
star-icons-4
House
Map-icon
like-icon10.0
Exceptional
(21 Reviews)
1 Bedroom 1 Bath 4 Guests 592.02 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£97/Night 7 Nights - £676
Villa
Map-icon
like-icon10.0
Exceptional
(33 Reviews)
1 Bedroom 1 Bath 4 Guests
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£119/Night 7 Nights - £834
Villa
Map-icon
like-icon10.0
Exceptional
(15 Reviews)
4 Bedrooms 2 Baths 10 Guests 1690 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£216/Night 7 Nights - £1,509
star-icons-4
Apartment
Map-icon
like-icon10.0
Exceptional
(19 Reviews)
1 Bedroom 1 Bath 3 Guests 484.38 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£124/Night 7 Nights - £871
Villa
Map-icon
like-icon10.0
Exceptional
(12 Reviews)
2 Bedrooms 2 Baths 6 Guests 775 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Ocean View
    Ocean View
More amenities
£195/Night 7 Nights - £1,362
Apartment
Map-icon
like-icon10.0
Exceptional
(3 Reviews)
3 Bedrooms 1 Bath 5 Guests
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£76/Night 7 Nights - £534
Villa
Map-icon
like-icon10.0
Exceptional
(2 Reviews)
4 Bedrooms 3 Baths 7 Guests 320 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£219/Night 7 Nights - £1,535

Mytilene Luxury Rentals

House
Map-icon
4 Bedrooms 2 Baths 8 Guests
  • Private Pool
    Private Pool
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£861/Night 7 Nights - £6,030
star-icons-4
Villa
Map-icon
like-icon10.0
Exceptional
(8 Reviews)
4 Bedrooms 2 Baths 8 Guests 2152.78 ft²
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
More amenities
£812/Night 7 Nights - £5,681
New
House
Map-icon
4 Bedrooms 5 Baths 8 Guests 3444 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£619/Night 7 Nights - £4,331
Villa
Map-icon
1 Bedroom 1 Bath
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
More amenities
£555/Night 7 Nights - £3,886
Villa
Map-icon
like-icon8.0
Excellent
(1 Review)
4 Bedrooms 4 Baths 8 Guests 4843.76 ft²
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
More amenities
£530/Night 7 Nights - £3,707
star-icons-3
Apartment
Map-icon
like-icon9.9
Exceptional
(21 Reviews)
1 Bedroom 1 Bath 4 Guests 699.65 ft²
  • View
    View
  • Parking
    Parking
More amenities
£490/Night 7 Nights - £3,433
Villa
Map-icon
like-icon10.0
Exceptional
(1 Review)
3 Bedrooms 3 Baths 6 Guests 1615 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£459/Night 7 Nights - £3,214
House
Map-icon
like-icon10.0
Exceptional
(1 Review)
3 Bedrooms 3 Baths 6 Guests 1593.06 ft²
  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
More amenities
£431/Night 7 Nights - £3,016

Mytilene Pet Friendly Vacation Rentals

House
Map-icon
like-icon8.0
Excellent
(1 Review)
3 Bedrooms 1 Bath 10 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
More amenities
£172/Night 7 Nights - £1,207
star-icons-3
Villa
Map-icon
like-icon10.0
Exceptional
(13 Reviews)
3 Bedrooms 3 Baths 8 Guests 1614.59 ft²
  • Balcony/Terrace
    Balcony/Terrace
  • View
    View
More amenities
£181/Night 7 Nights - £1,264
star-icons-4
Apartment
Map-icon
like-icon8.4
Excellent
(82 Reviews)
1 Bedroom 1 Bath 2 Guests
  • Pool
    Pool
  • Ocean View
    Ocean View
More amenities
£111/Night 7 Nights - £777
Apartment
Map-icon
like-icon8.0
Excellent
(1 Review)
1 Bedroom 1 Bath 2 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
More amenities
£99/Night 7 Nights - £693
star-icons-4
Apartment
Map-icon
like-icon10.0
Exceptional
(7 Reviews)
1 Bedroom 1 Bath 2 Guests 592.02 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£64/Night 7 Nights - £447
Villa
Map-icon
3 Bedrooms 2 Baths 5 Guests 915 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£261/Night 7 Nights - £1,824
Villa
Map-icon
3 Bedrooms 2 Baths 6 Guests
  • Private Pool
    Private Pool
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£229/Night 7 Nights - £1,600
Villa
Map-icon
3 Bedrooms 2 Baths 8 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£186/Night 7 Nights - £1,301

Mytilene Large Vacation Homes

Villa
Map-icon
like-icon10.0
Exceptional
(1 Review)
1 Bedroom 1 Bath 4 Guests 592 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£174/Night 7 Nights - £1,220
star-icons-4
Villa
Map-icon
like-icon10.0
Exceptional
(10 Reviews)
3 Bedrooms 3 Baths 6 Guests 1829.86 ft²
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£337/Night 7 Nights - £2,362
Villa
Map-icon
3 Bedrooms 2 Baths 6 Guests
  • Private Pool
    Private Pool
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£248/Night 7 Nights - £1,738
star-icons-4
Villa
Map-icon
like-icon10.0
Exceptional
(4 Reviews)
2 Bedrooms 2 Baths 5 Guests 1399.31 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£209/Night 7 Nights - £1,463
Villa
Map-icon
2 Bedrooms 1 Bath 4 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Air Conditioner
    Air Conditioner
More amenities
£226/Night 7 Nights - £1,582
Villa
Map-icon
3 Bedrooms 2 Baths 6 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£196/Night 7 Nights - £1,371
Villa
Map-icon
1 Bedroom 1 Bath 3 Guests
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£174/Night 7 Nights - £1,217
Villa
Map-icon
1 Bedroom 1 Bath 3 Guests
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£174/Night 7 Nights - £1,217

Why Choose Rent By Owner for your Mytilene Vacation Rental Homes?

What makes our Vacation Rentals special?

image
Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
image
Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
image
Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Mytilene

When should you plan your Vacation Rentals stay?

Choosing the optimal time to visit this destination ensures you experience its unique charm at its finest, whether you're seeking warm summer days or a more peaceful off-season getaway within the North Aegean Islands.

Peak Season Highlights

spring
July to August

During the summer months, this destination experiences its peak season with warm weather and lively local events, making it ideal for those seeking vibrant outdoor activities and beach relaxation.

Average Temperature Daytime: 30°C - Nighttime: 22°C
spring
June to September

The most popular travel period spans from early summer to early autumn, offering extended sunshine and ideal conditions for exploring the region's scenic coastal areas and cultural sites.

Average Temperature Daytime: 28°C - Nighttime: 20°C

Off-Season Highlights

image
March to May

In the spring, the area sees fewer visitors, providing a quieter setting with mild weather that is perfect for relaxing strolls and discovering local charm without the crowds.

Average Temperature Daytime: 18°C - Nighttime: 12°C
image
October to November

Autumn offers cooler temperatures and fewer tourists, making it an excellent time for leisurely explorations and enjoying the region's natural beauty before winter sets in.

Average Temperature Daytime: 20°C - Nighttime: 14°C

Weekly Weather Forecast for Mytilene

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy a private outdoor dining area perfect for alfresco meals with scenic views of the surrounding landscape.
  • Relax in a spacious garden or courtyard to unwind and soak up the Mediterranean sunshine.
  • Make use of a well-maintained barbecue grill for outdoor cooking during your stay here.
  • Take advantage of outdoor seating arrangements designed for lounging or socializing with family and friends.
  • Discover a charming patio or veranda that provides a peaceful space to enjoy morning coffee or evening sunsets.
  • Benefit from access to a swimming pool surrounded by lush greenery, ideal for refreshing dips on warm days.
  • Utilize nearby outdoor recreational facilities such as hiking trails or cycle paths that explore this region’s natural beauty.
image
image

Family Activities

  • Visit the Archaeological Museum of Mytilene: Discover ancient artifacts and exhibits that offer a fascinating glimpse into the region's rich history, perfect for engaging family learning experiences.
  • Explore the local beaches near Lesvos: Relax and enjoy sunny days on pristine shores that provide ideal spots for picnicking, swimming, and building sandcastles with your loved ones.
  • Stroll through the scenic town center of Mytilene: Wander along charming streets lined with traditional cafes and shops, offering a relaxed atmosphere for family outings and sightseeing.
  • Take a boat tour from the harbor: Experience the surrounding Aegean Sea on a family-friendly cruise, providing stunning views and memorable moments within this beautiful region.
image

Adult Activities

  • Explore the Archaeological Museum of Mytilene: Dive into the region’s rich history and discover ancient artifacts that tell the story of this captivating destination.
  • Discover the vibrant local markets: Stroll through bustling markets to experience authentic flavors, handcrafted goods, and the lively atmosphere characteristic of here.
  • Relax at the scenic promenade: Take a leisurely walk along the waterfront and enjoy stunning views of the Aegean Sea, perfect for unwinding after a day of exploring.
  • Enjoy a wine tasting tour: Sample acclaimed local wines in nearby vineyards and gain insight into the region’s celebrated viticulture traditions.

Mytilene Travel Tips

How Can You Make the Most of Your Stay?

  • Explore local cuisine: Take time to savor the authentic flavors of this destination’s renowned tavernas and eateries, available near your vacation rentals, to truly experience the region’s culinary heritage.
  • Visit historical sites: Incorporate visits to the area’s rich history by exploring nearby archaeological sites and museums, ensuring you get a deeper understanding of this destination’s cultural significance.
  • Plan outdoor activities: Make the most of the natural beauty here by engaging in outdoor pursuits such as walking along scenic coastlines or discovering hidden spots that are easily accessible from your vacation rental.
  • Choose centrally located accommodations: To maximize your time and convenience, select vacation rentals situated close to key attractions and transportation options within the region.

Transportation Options

  • Local Buses: The bus network offers an affordable and convenient way to explore the area, connecting you to key points around the city and beyond.
  • Taxis: Taxis provide quick and direct transportation options for personalized travel within the region, ideal for reaching destinations on your schedule.
  • Car Rentals: Renting a car offers flexibility and independence, allowing you to discover remote beaches and scenic spots at your own pace.
  • Ferry Services: Ferries are available for travel between islands and to nearby ports, making them a practical choice for island-hopping adventures.

Local Customs Options

  • Offering Hospitality with Philoxenia: Locals here are renowned for their warm and welcoming hospitality, making your stay memorable and authentic.
  • Celebrating Local Festivals: Participating in the region's traditional festivals provides a unique glimpse into its rich cultural heritage and communal spirit.
  • Practicing Respect for Religious Sites: When visiting churches and monasteries, it’s customary to observe proper decorum and dress modestly, reflecting the area's spiritual traditions.
  • Engaging in Traditional Cuisine: Sharing meals that feature local ingredients and recipes is a cherished custom that enhances your cultural experience here.

Frequently Asked Questions About Mytilene?

1. What are the top vacation rentals in Mytilene?

2. How many vacation rentals have private pools in Mytilene?

There are 4 vacation rentals with private pools near Mytilene. Top-rated RBO homes that have access to a swimming pool include:

3. Which vacation homes in Mytilene are best for families?

If you are looking for a family-friendly vacation home in Mytilene, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Mytilene:

4. How many Rentbyowner vacation rentals are available in Mytilene?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 460 in the Mytilene area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Mytilene. 

5. What is the cancellation policy for my vacation rental booking in Mytilene?

The cancellation policy varies depending on the property listing. You should review the specific terms outlined in the listing details or contact the property owner directly to understand the cancellation timeframe and any potential fees.

6. How do I confirm my reservation at a rental property in Lesvos?

Reservations are confirmed once you complete the booking process on the listing page and receive a confirmation email. For any special requests or clarifications, reaching out to the property owner through the platform can help ensure your stay is secured.

7. Are there any additional fees associated with booking a vacation rental in North Aegean Islands?

Additional charges such as cleaning fees, service fees, or local taxes may apply depending on the property. These will be clearly indicated in the listing before you finalize your reservation, so review all details carefully.

8. What amenities are typically included in vacation rentals here?

Most listings include essential amenities like Wi-Fi, kitchen facilities, and linens. To find out about specific features or extras, check the property description or contact the owner directly for clarification.

9. Can I modify or cancel my booking after confirming it in this area?

Modification or cancellation policies depend on the individual property’s rules. It’s recommended to review the cancellation and amendment terms in the listing and communicate directly with the owner if you need assistance or special arrangements.

Mytilene Top Rated Vacation Rentals

House
Map-icon
like-icon10.0
Exceptional
(15 Reviews)
1 Bedroom 1 Bath
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£46/Night 7 Nights - £320
star-icons-4
Villa
Map-icon
like-icon9.8
Exceptional
(4 Reviews)
4 Bedrooms 3 Baths 8 Guests 1937.5 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£297/Night 7 Nights - £2,082
star-icons-4
Apartment
Map-icon
like-icon9.7
Exceptional
(285 Reviews)
10 Bedrooms 2 Baths 8 Guests 365.97 ft²
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
More amenities
£92/Night 7 Nights - £647
star-icons-4
House
Map-icon
like-icon9.7
Exceptional
(48 Reviews)
9 Bedrooms 6 Baths 17 Guests 1399.31 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£88/Night 7 Nights - £617
star-icons-4
Hotel
Map-icon
like-icon9.6
Exceptional
(162 Reviews)
1 Bath
  • Hot Tub
    Hot Tub
  • Spa
    Spa
More amenities
£118/Night 7 Nights - £825
star-icons-4
Villa
Map-icon
like-icon9.5
Exceptional
(213 Reviews)
6 Bedrooms 6 Baths 22 Guests 570.49 ft²
  • Oceanfront
    Oceanfront
  • Fireplace/Heating
    Fireplace/Heating
More amenities
£141/Night 7 Nights - £985
House
Map-icon
like-icon9.4
Exceptional
(29 Reviews)
1 Bedroom 1 Bath
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
More amenities
£86/Night 7 Nights - £604
star-icons-3
Hotel
Map-icon
like-icon9.4
Exceptional
(14 Reviews)
1 Bath
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
More amenities
£56/Night 7 Nights - £393